br in different international journals
in different international journals and conferences. He has published more than 120 articles in international journals and conference proceedings. He holds the program chair in many conferences in the fields of decision making analysis, big data, optimization, complexity and the internet of things, as well as editorial collaboration in some journals of high impact.
Mai Mohamed Received her BS degree and master degree from Zagazig University, faculty of computers and infor-matics,Egypt . Her current research interests are com-putation intelligence, neural networks, and Neutrosophic logic.
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Science of the Total Environment
A novel approach to evaluate the lung cancer risk of airborne particles emitted in a city
a Department of Civil and Mechanical Engineering, University of Cassino and Southern Lazio, Cassino, FR, Italy
b Department of Economics, Engineering, Society and Business Organization, Tuscia University, Viterbo, Italy
c Department of Civil and Environmental Engineering and Architecture, University of Cagliari, Cagliari, Italy
d Department of Engineering, University “Parthenope”, Naples, Italy
e Queensland University of Technology, Brisbane, Australia
• Evaluation of the particle-related lung
cancer risk emitted by the city.
• Evaluation of the risk emitted by the dif-ferent sources as new cases of lung can-cer.
• Source apportionment of the lung can-cer risk emitted by the different sources. • The main metric contributing to the emitted risk is the particle surface area. • The Sotrastaurin (AEB071) mainly contributing to the risk is the As (vehicular traffic marker).
Editor: Pavlos Kassomenos
Lung cancer risk
Ultrafine particles PM10 Particle surface area
Air quality still represents a main threat to human health in cities. Even in developed countries, decades of air pol-lution control not yet allowed to reduce pollutant concentrations in urban areas adequately. Indeed, high air-borne particle concentrations are measured in several European cities; prophase is a main issue since particles represent a carrier for carcinogenic compounds. Numerous researches measuring the exposure to the different aerosol metrics in urban areas were recently performed, nonetheless, few data on the lung cancer risk in such en-vironments are available.
In the present paper a novel approach to evaluate the lung cancer risk related to the airborne particles emitted by the different sources located in a city is proposed and applied to a pilot case-study (i.e. an Italian city). In partic-ular, an existing lung cancer risk model was modified and applied to assess the particle-related lung cancer “emit-ted” by the different sources of the city using pollutant emission factors provided by accredited emission inventory databases. Therefore, the average toxicity of the particles emitted by the city (i.e. lung cancer slope fac-tor) and the lung cancer risk globally emitted by the city, expressed as new cases of lung cancer, were evaluated. The proposed emission inventory also allowed to identify and localize the main contributors to the overall risk emitted in a city. As an example, for the city under investigation, the research revealed that the main contributor, amongst the sources considered, is the vehicular traffic which is characterized by a lower mass fraction of carci-nogenic compounds but a much higher sub-micron particle emission with respect to the other sources.
Corresponding author at: Department of Civil and Mechanical Engineering, University of Cassino and Southern Lazio, Via Di Biasio 43, 03043 Cassino, FR, Italy. E-mail address: [email protected] (L. Stabile).